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dc.contributor.authorWest, Catharine M Len
dc.contributor.authorDavidson, Susan Een
dc.contributor.authorPool, Claireen
dc.contributor.authorJames, Roger Den
dc.contributor.authorSchofield, Philip Fen
dc.date.accessioned2010-07-27T15:35:45Z
dc.date.available2010-07-27T15:35:45Z
dc.date.issued1991-05
dc.identifier.citationLack of a relationship between colony-forming efficiency and surviving fraction at 2 Gy. 1991, 126 (2):260-3 Radiat. Res.en
dc.identifier.issn0033-7587
dc.identifier.pmid2023996
dc.identifier.urihttp://hdl.handle.net/10541/108457
dc.description.abstractThe relationship between in vitro radiation sensitivity and colony-forming efficiency has been examined for primary human tumors of the cervix, colorectum, and lymph gland. Tumors were cultured using the Courtenay-Mills soft agar clonogenic assay and radiosensitivity was assessed as surviving fraction at 2 Gy. There was no correlation between colony-forming efficiency and surviving fraction at 2 Gy, giving confidence to the use of surviving fraction at 2 Gy as a predictor of clinical outcome.
dc.language.isoenen
dc.subjectCanceren
dc.subjectColonic Canceren
dc.subjectRectal Canceren
dc.subjectTumour Stem Cell Assayen
dc.subjectUterine Cervical Canceren
dc.subject.meshCell Survival
dc.subject.meshCesium Radioisotopes
dc.subject.meshColonic Neoplasms
dc.subject.meshFemale
dc.subject.meshGamma Rays
dc.subject.meshHumans
dc.subject.meshNeoplasms
dc.subject.meshRectal Neoplasms
dc.subject.meshTumor Stem Cell Assay
dc.subject.meshUterine Cervical Neoplasms
dc.titleLack of a relationship between colony-forming efficiency and surviving fraction at 2 Gy.en
dc.typeArticleen
dc.contributor.departmentCancer Research Campaign Department of Radiobiology, Paterson Institute for Cancer Research, Manchester, United Kingdom.en
dc.identifier.journalRadiation Researchen
html.description.abstractThe relationship between in vitro radiation sensitivity and colony-forming efficiency has been examined for primary human tumors of the cervix, colorectum, and lymph gland. Tumors were cultured using the Courtenay-Mills soft agar clonogenic assay and radiosensitivity was assessed as surviving fraction at 2 Gy. There was no correlation between colony-forming efficiency and surviving fraction at 2 Gy, giving confidence to the use of surviving fraction at 2 Gy as a predictor of clinical outcome.


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