Lack of a relationship between colony-forming efficiency and surviving fraction at 2 Gy.
AffiliationCancer Research Campaign Department of Radiobiology, Paterson Institute for Cancer Research, Manchester, United Kingdom.
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AbstractThe relationship between in vitro radiation sensitivity and colony-forming efficiency has been examined for primary human tumors of the cervix, colorectum, and lymph gland. Tumors were cultured using the Courtenay-Mills soft agar clonogenic assay and radiosensitivity was assessed as surviving fraction at 2 Gy. There was no correlation between colony-forming efficiency and surviving fraction at 2 Gy, giving confidence to the use of surviving fraction at 2 Gy as a predictor of clinical outcome.
CitationLack of a relationship between colony-forming efficiency and surviving fraction at 2 Gy. 1991, 126 (2):260-3 Radiat. Res.
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