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dc.contributor.authorHartley, Ann L
dc.contributor.authorBirch, Jillian M
dc.contributor.authorBlair, Val
dc.date.accessioned2010-07-27T12:38:12Z
dc.date.available2010-07-27T12:38:12Z
dc.date.issued1991-03
dc.identifier.citationMalignant disease in the mothers of a population-based series of young adults with bone and soft tissue sarcomas. 1991, 63 (3):416-9 Br. J. Canceren
dc.identifier.issn0007-0920
dc.identifier.pmid2003983
dc.identifier.urihttp://hdl.handle.net/10541/108424
dc.description.abstractMothers of a population-based series of young adults with bone and soft tissue sarcoma were traced and their cancer risks estimated. No overall excess of cancers compared with expected numbers calculated from population rates was seen but mothers of patients with synovial sarcoma had significantly more cancers than expected and this was accounted for mainly by an excess of breast cancer. In addition there were strong indications that a proportion of cases were members of families with inherited cancer-prone syndromes, in particular with neurofibromatosis or with the Li Fraumeni cancer family syndrome.
dc.language.isoenen
dc.subjectCanceren
dc.subjectBone Canceren
dc.subjectSoft Tissue Canceren
dc.subject.meshAdolescent
dc.subject.meshAdult
dc.subject.meshBone Neoplasms
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshMothers
dc.subject.meshNeoplasms
dc.subject.meshRisk
dc.subject.meshSarcoma
dc.subject.meshSoft Tissue Neoplasms
dc.titleMalignant disease in the mothers of a population-based series of young adults with bone and soft tissue sarcomas.en
dc.typeArticleen
dc.contributor.departmentCancer Research Campaign, Christie Hospital and Holt Radium Institute, Manchester, UK.en
dc.identifier.journalBritish Journal of Canceren
html.description.abstractMothers of a population-based series of young adults with bone and soft tissue sarcoma were traced and their cancer risks estimated. No overall excess of cancers compared with expected numbers calculated from population rates was seen but mothers of patients with synovial sarcoma had significantly more cancers than expected and this was accounted for mainly by an excess of breast cancer. In addition there were strong indications that a proportion of cases were members of families with inherited cancer-prone syndromes, in particular with neurofibromatosis or with the Li Fraumeni cancer family syndrome.


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