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dc.contributor.authorHarris, Martin
dc.contributor.authorHartley, Ann L
dc.contributor.authorBlair, Val
dc.contributor.authorBirch, Jillian M
dc.contributor.authorBanerjee, Saumitra S
dc.contributor.authorFreemont, A J
dc.contributor.authorMcClure, J
dc.contributor.authorMcWilliam, L J
dc.date.accessioned2010-07-27T12:31:58Z
dc.date.available2010-07-27T12:31:58Z
dc.date.issued1991-08
dc.identifier.citationSarcomas in north west England: I. Histopathological peer review. 1991, 64 (2):315-20 Br. J. Canceren
dc.identifier.issn0007-0920
dc.identifier.pmid1892759
dc.identifier.urihttp://hdl.handle.net/10541/108422
dc.description.abstractA total of 468 cases of bone, soft tissue and visceral sarcomas (and certain other tumours) diagnosed during the years 1982-84 in North West England were entered in a study of histopathological peer review, incidence and survival. This paper describes the effects of peer review. Material was reviewed by a panel of five pathologists for 413 of the 450 cases originally registered as sarcomas with the Regional Cancer Registry. The diagnosis of sarcomas was confirmed in 76% cases and and there was agreement on sub-type for 53% cases. Measures of agreement were lowest for the two sub-types most commonly diagnosed i.e. malignant fibrous histiocytoma and leiomyosarcoma. Degree of agreement between individual pathologists and final panel diagnosis was also very variable but never less than 65%. It is concluded that second opinion is essential in cases of presumed sarcomas for studies of incidence and aetiology and to ensure that appropriate treatment is selected.
dc.language.isoenen
dc.subjectBone Canceren
dc.subjectSoft Tissue Canceren
dc.subject.meshBone Neoplasms
dc.subject.meshEngland
dc.subject.meshHumans
dc.subject.meshPeer Review
dc.subject.meshSarcoma
dc.subject.meshSoft Tissue Neoplasms
dc.titleSarcomas in north west England: I. Histopathological peer review.en
dc.typeArticleen
dc.contributor.departmentDepartment of Pathology, Christie Hospital and Holt Radium Institute, Manchester, UK.en
dc.identifier.journalBritish Journal of Canceren
html.description.abstractA total of 468 cases of bone, soft tissue and visceral sarcomas (and certain other tumours) diagnosed during the years 1982-84 in North West England were entered in a study of histopathological peer review, incidence and survival. This paper describes the effects of peer review. Material was reviewed by a panel of five pathologists for 413 of the 450 cases originally registered as sarcomas with the Regional Cancer Registry. The diagnosis of sarcomas was confirmed in 76% cases and and there was agreement on sub-type for 53% cases. Measures of agreement were lowest for the two sub-types most commonly diagnosed i.e. malignant fibrous histiocytoma and leiomyosarcoma. Degree of agreement between individual pathologists and final panel diagnosis was also very variable but never less than 65%. It is concluded that second opinion is essential in cases of presumed sarcomas for studies of incidence and aetiology and to ensure that appropriate treatment is selected.


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