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dc.contributor.authorHrubisko, M
dc.contributor.authorMcGown, Alan T
dc.contributor.authorPrendiville, Joseph A
dc.contributor.authorRadford, John A
dc.contributor.authorThatcher, Nick
dc.contributor.authorFox, Brian W
dc.date.accessioned2010-07-22T09:04:03Z
dc.date.available2010-07-22T09:04:03Z
dc.date.issued1992
dc.identifier.citationSuitability of cisplatin solutions for 14-day continuous infusion by ambulatory pump. 1992, 29 (3):252-5 Cancer Chemother Pharmacolen
dc.identifier.issn0344-5704
dc.identifier.pmid1733559
dc.identifier.doi10.1007/BF00686261
dc.identifier.urihttp://hdl.handle.net/10541/108141
dc.description.abstractThe stability of cisplatin (DDP) solutions (1 and 1.6 mg/ml in saline-mannitol) in plastic infusion bags was studied for up to 14 days at 25 degrees C, 37 degrees C and 60 degrees C. Small changes in the solution were observed, but no evidence of any decomposition product was seen. Some precipitation of DDP was seen in the 1.6-mg/ml solution at the lower temperatures. Fluid loss from the bags was significant at the higher temperatures.
dc.language.isoenen
dc.subject.meshChromatography, High Pressure Liquid
dc.subject.meshCisplatin
dc.subject.meshDrug Stability
dc.subject.meshInfusion Pumps
dc.subject.meshSolutions
dc.subject.meshTemperature
dc.subject.meshTime Factors
dc.titleSuitability of cisplatin solutions for 14-day continuous infusion by ambulatory pump.en
dc.typeArticleen
dc.contributor.departmentCancer Research Institute, Slovak Academy of Sciences, Bratislava.en
dc.identifier.journalCancer Chemotherapy and Pharmacologyen
html.description.abstractThe stability of cisplatin (DDP) solutions (1 and 1.6 mg/ml in saline-mannitol) in plastic infusion bags was studied for up to 14 days at 25 degrees C, 37 degrees C and 60 degrees C. Small changes in the solution were observed, but no evidence of any decomposition product was seen. Some precipitation of DDP was seen in the 1.6-mg/ml solution at the lower temperatures. Fluid loss from the bags was significant at the higher temperatures.


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