24-hour cyclophosphamide infusion therapy for malignant mesothelioma of the pleura.
dc.contributor.author | Anderson, Heather | |
dc.contributor.author | Hasleton, Philip S | |
dc.contributor.author | Michie, A B | |
dc.contributor.author | Johnson, Richard J | |
dc.contributor.author | Thatcher, Nick | |
dc.date.accessioned | 2010-07-21T15:17:53Z | |
dc.date.available | 2010-07-21T15:17:53Z | |
dc.date.issued | 1988-01 | |
dc.identifier.citation | 24-hour cyclophosphamide infusion therapy for malignant mesothelioma of the pleura. 1988, 82 (1):64-9 Br J Dis Chest | en |
dc.identifier.issn | 0007-0971 | |
dc.identifier.pmid | 3166920 | |
dc.identifier.doi | 10.1016/0007-0971(88)90009-5 | |
dc.identifier.uri | http://hdl.handle.net/10541/108101 | |
dc.description.abstract | Thirteen patients with malignant mesothelioma of the pleura have been treated with 24-hour cyclophosphamide infusion (2.5 g/m2) therapy. There were no complete responders. Three patients (23%) had a partial response, and a further three patients who did not fulfil the criteria for objective response, had subjective benefit from therapy with increase in performance status. The overall median survival from the onset of therapy was 6 months (range 2-19 months). High dose cyclophosphamide offers no advantage over standard dose therapy. | |
dc.language.iso | en | en |
dc.subject | Pleural Cancer | en |
dc.subject.mesh | Adult | |
dc.subject.mesh | Aged | |
dc.subject.mesh | Cyclophosphamide | |
dc.subject.mesh | Drug Administration Schedule | |
dc.subject.mesh | Female | |
dc.subject.mesh | Humans | |
dc.subject.mesh | Infusions, Parenteral | |
dc.subject.mesh | Lung | |
dc.subject.mesh | Male | |
dc.subject.mesh | Mesothelioma | |
dc.subject.mesh | Middle Aged | |
dc.subject.mesh | Pleural Neoplasms | |
dc.title | 24-hour cyclophosphamide infusion therapy for malignant mesothelioma of the pleura. | en |
dc.contributor.department | CRC Department of Medical Oncology, Christie Hospital, Manchester. | en |
dc.identifier.journal | British Journal of Diseases of the Chest | en |
html.description.abstract | Thirteen patients with malignant mesothelioma of the pleura have been treated with 24-hour cyclophosphamide infusion (2.5 g/m2) therapy. There were no complete responders. Three patients (23%) had a partial response, and a further three patients who did not fulfil the criteria for objective response, had subjective benefit from therapy with increase in performance status. The overall median survival from the onset of therapy was 6 months (range 2-19 months). High dose cyclophosphamide offers no advantage over standard dose therapy. |