24-hour cyclophosphamide infusion therapy for malignant mesothelioma of the pleura.
AffiliationCRC Department of Medical Oncology, Christie Hospital, Manchester.
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AbstractThirteen patients with malignant mesothelioma of the pleura have been treated with 24-hour cyclophosphamide infusion (2.5 g/m2) therapy. There were no complete responders. Three patients (23%) had a partial response, and a further three patients who did not fulfil the criteria for objective response, had subjective benefit from therapy with increase in performance status. The overall median survival from the onset of therapy was 6 months (range 2-19 months). High dose cyclophosphamide offers no advantage over standard dose therapy.
Citation24-hour cyclophosphamide infusion therapy for malignant mesothelioma of the pleura. 1988, 82 (1):64-9 Br J Dis Chest
JournalBritish Journal of Diseases of the Chest