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Lack of effect of immunotherapy with BCG and Corynebacterium parvum on hepatic drug hydroxylation in man.

dc.contributor.authorWan, H H
dc.contributor.authorThatcher, Nick
dc.contributor.authorMullen, P W
dc.contributor.authorSmith, G N
dc.contributor.authorWilkinson, Peter M
dc.date.accessioned2010-07-21T14:50:38Z
dc.date.available2010-07-21T14:50:38Z
dc.date.issued1979-04
dc.identifier.citationLack of effect of immunotherapy with BCG and Corynebacterium parvum on hepatic drug hydroxylation in man. 1979, 39 (4):441-4 Br. J. Canceren
dc.identifier.issn0007-0920
dc.identifier.pmid444399
dc.identifier.urihttp://hdl.handle.net/10541/108089
dc.description.abstractSerial serum diphenylhydantoin and urinary 5-(p-hydroxphenyl)-5-phenylhydantoin concentrations were determined in 8 patients with malignant disease and 4 healthy volunteers on 2 separate occasions after an oral dose of diphenylhydantoin (500 mg). No significant difference was observed between metabolism before and 10 days after immunization with BCG or Corynebacterium parvum. Volunteers without intervening immunization similarly showed no difference.
dc.language.isoenen
dc.subjectKidney Canceren
dc.subjectCancer Metastasisen
dc.subjectRectal Canceren
dc.subject.meshAdenocarcinoma
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshBCG Vaccine
dc.subject.meshBacterial Vaccines
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshImmunotherapy
dc.subject.meshKidney Neoplasms
dc.subject.meshLiver
dc.subject.meshMale
dc.subject.meshMelanoma
dc.subject.meshMiddle Aged
dc.subject.meshNeoplasm Metastasis
dc.subject.meshPhenytoin
dc.subject.meshPropionibacterium acnes
dc.subject.meshRectal Neoplasms
dc.titleLack of effect of immunotherapy with BCG and Corynebacterium parvum on hepatic drug hydroxylation in man.en
dc.typeArticleen
dc.contributor.departmentChristie Hospital and Holt Radium Institute, Manchester.en
dc.identifier.journalBritish journal of canceren
html.description.abstractSerial serum diphenylhydantoin and urinary 5-(p-hydroxphenyl)-5-phenylhydantoin concentrations were determined in 8 patients with malignant disease and 4 healthy volunteers on 2 separate occasions after an oral dose of diphenylhydantoin (500 mg). No significant difference was observed between metabolism before and 10 days after immunization with BCG or Corynebacterium parvum. Volunteers without intervening immunization similarly showed no difference.


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