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Pulmonary carcinoid tumours: a clinico-pathological study of 35 cases.

dc.contributor.authorHasleton, Philip S
dc.contributor.authorGomm, S
dc.contributor.authorBlair, Val
dc.contributor.authorThatcher, Nick
dc.date.accessioned2010-07-21T10:08:31Z
dc.date.available2010-07-21T10:08:31Z
dc.date.issued1986-12
dc.identifier.citationPulmonary carcinoid tumours: a clinico-pathological study of 35 cases. 1986, 54 (6):963-7 Br. J. Canceren
dc.identifier.issn0007-0920
dc.identifier.pmid3801292
dc.identifier.urihttp://hdl.handle.net/10541/108006
dc.description.abstractA clinico-pathological study of 35 bronchial carcinoid tumours was undertaken. Age, T stage, N stage, lymph node involvement, number of lymph nodes involved and number of cigarettes smoked per day were the clinical variables affecting survival. The histological variables related to survival were; mitotic count, necrosis, nuclear pleomorphism, vascular and lymphatic permeation and an undifferentiated growth pattern. All these features could be detected with routine histological stains, whereas immunocytochemical methods for demonstrating neuron specific enolase were of no help in assessing the prognosis. However there was a tendency for a well differentiated neuroendocrine carcinoma to stain strongly in some areas with carcinoembryonic antigen.
dc.language.isoenen
dc.subjectBronchial Canceren
dc.subjectCarcinoid Tumouren
dc.subjectCancer Stagingen
dc.subject.meshAdenoma
dc.subject.meshAdolescent
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshBronchial Neoplasms
dc.subject.meshCarcinoembryonic Antigen
dc.subject.meshCarcinoid Tumor
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshLymphatic Metastasis
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshMitosis
dc.subject.meshNeoplasm Staging
dc.subject.meshPrognosis
dc.subject.meshSmoking
dc.titlePulmonary carcinoid tumours: a clinico-pathological study of 35 cases.en
dc.typeArticleen
dc.contributor.departmentDepartment of Pathology, Wythenshawe Hospital, Manchester M23 9LT.en
dc.identifier.journalBritish Journal of Canceren
html.description.abstractA clinico-pathological study of 35 bronchial carcinoid tumours was undertaken. Age, T stage, N stage, lymph node involvement, number of lymph nodes involved and number of cigarettes smoked per day were the clinical variables affecting survival. The histological variables related to survival were; mitotic count, necrosis, nuclear pleomorphism, vascular and lymphatic permeation and an undifferentiated growth pattern. All these features could be detected with routine histological stains, whereas immunocytochemical methods for demonstrating neuron specific enolase were of no help in assessing the prognosis. However there was a tendency for a well differentiated neuroendocrine carcinoma to stain strongly in some areas with carcinoembryonic antigen.


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