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    A phase II study of ifosfamide and a2b-interferon in advanced non-small-cell lung cancer.

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    Authors
    Lind, Michael J
    Gomm, S
    Simmonds, A P
    Ashcroft, Linda
    Kamthan, A
    Gurney, H
    Thatcher, Nick
    Affiliation
    CRC Department of Medical Oncology, Christie Hospital, Manchester, U.K.
    Issue Date
    1991
    
    Metadata
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    Abstract
    A total of 45 patients with advanced non-small-cell lung cancer were treated with a combination of 1.5 g/m2 ifosfamide given on days 1-5 every 3 weeks for four courses with 3 million IU a2b-interferon (Intron A) given s.c. three times a week for 12 weeks. Nine objective responses were seen, including two complete responses (CRs) and seven partial responses (PRs). Haematological and non-haematological toxicities were generally mild and did not necessitate discontinuation of therapy.
    Citation
    A phase II study of ifosfamide and a2b-interferon in advanced non-small-cell lung cancer. 1991, 28 (2):142-4 Cancer Chemother Pharmacol
    Journal
    Cancer Chemotherapy and Pharmacology
    URI
    http://hdl.handle.net/10541/107811
    DOI
    10.1007/BF00689705
    PubMed ID
    1647893
    Type
    Article
    Language
    en
    ISSN
    0344-5704
    ae974a485f413a2113503eed53cd6c53
    10.1007/BF00689705
    Scopus Count
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