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dc.contributor.authorHarvie, Michelle N
dc.contributor.authorCampbell, I T
dc.contributor.authorThatcher, Nick
dc.contributor.authorBaildam, Andrew D
dc.date.accessioned2010-07-12T15:43:25Z
dc.date.available2010-07-12T15:43:25Z
dc.date.issued2003-10
dc.identifier.citationChanges in body composition in men and women with advanced nonsmall cell lung cancer (NSCLC) undergoing chemotherapy. 2003, 16 (5):323-6 J Hum Nutr Dieten
dc.identifier.issn0952-3871
dc.identifier.pmid14516379
dc.identifier.urihttp://hdl.handle.net/10541/107471
dc.description.abstractBACKGROUND: Men with nonsmall cell lung cancer (NSCLC) are more susceptible to weight loss than women. The composition and aetiology of these gender specific weight changes are not known. METHODS: Measurements of body mass, body composition and energy balance (resting energy expenditure and energy intake) were made in 15 men and six women before and after chemotherapy for NSCLC. RESULTS: Over the course of chemotherapy minimal weight change was observed in both men and women. Men increased body fat from 25.0 +/- 5.5 to 27.9 +/- 7.9% (P < 0.05) whereas fat free mass (FFM) tended to decrease (P = 0.063). There was no change in body fat or FFM in the women. In the men resting energy expenditure decreased over the course of chemotherapy from 113.2 +/- 15.9 to 105.1 +/- 10.1% of the value predicted from the Harris Benedict equation (P < 0.05). In the women resting energy expenditure (REE) did not alter. CONCLUSION: Over the course of chemotherapy for NSCLC, men and women appear to have different patterns of change in body composition and in energy expenditure.
dc.language.isoenen
dc.subjectLung Canceren
dc.subject.meshAdipose Tissue
dc.subject.meshAntineoplastic Agents
dc.subject.meshBody Composition
dc.subject.meshCarcinoma, Non-Small-Cell Lung
dc.subject.meshEnergy Intake
dc.subject.meshEnergy Metabolism
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshLung Neoplasms
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshMuscle, Skeletal
dc.subject.meshProspective Studies
dc.subject.meshSex Factors
dc.titleChanges in body composition in men and women with advanced nonsmall cell lung cancer (NSCLC) undergoing chemotherapy.en
dc.typeArticleen
dc.contributor.departmentUniversity Departments of Anaesthesia Medical Oncology Surgery, South Manchester University Hospitals NHS Trust, Manchester M20 2LR, UK. m_harvie@fs1.with.man.ac.uken
dc.identifier.journalJournal of human nutrition and dietetics : the official journal of the British Dietetic Associationen
html.description.abstractBACKGROUND: Men with nonsmall cell lung cancer (NSCLC) are more susceptible to weight loss than women. The composition and aetiology of these gender specific weight changes are not known. METHODS: Measurements of body mass, body composition and energy balance (resting energy expenditure and energy intake) were made in 15 men and six women before and after chemotherapy for NSCLC. RESULTS: Over the course of chemotherapy minimal weight change was observed in both men and women. Men increased body fat from 25.0 +/- 5.5 to 27.9 +/- 7.9% (P < 0.05) whereas fat free mass (FFM) tended to decrease (P = 0.063). There was no change in body fat or FFM in the women. In the men resting energy expenditure decreased over the course of chemotherapy from 113.2 +/- 15.9 to 105.1 +/- 10.1% of the value predicted from the Harris Benedict equation (P < 0.05). In the women resting energy expenditure (REE) did not alter. CONCLUSION: Over the course of chemotherapy for NSCLC, men and women appear to have different patterns of change in body composition and in energy expenditure.


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