• Login
    View Item 
    •   Home
    • The Manchester Institute Cancer Research UK
    • All Paterson Institute for Cancer Research
    • View Item
    •   Home
    • The Manchester Institute Cancer Research UK
    • All Paterson Institute for Cancer Research
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of ChristieCommunitiesTitleAuthorsIssue DateSubmit DateSubjectsThis CollectionTitleAuthorsIssue DateSubmit DateSubjects

    My Account

    LoginRegister

    Local Links

    The Christie WebsiteChristie Library and Knowledge Service

    Statistics

    Display statistics

    Medicinal plants in tropical medicine. 2. Natural products in cancer treatment from bench to the clinic.

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Authors
    Fox, Brian W
    Affiliation
    Paterson Institute for Cancer Research, Christie Hospital, Withington, Manchester, UK.
    Issue Date
    1991
    
    Metadata
    Show full item record
    Abstract
    The development of anticancer agents has, in the past, relied heavily on leads derived from screening a wide variety of agents from both synthetic and natural sources. With the development of new techniques of measurement of biochemical changes in cells and the advent of molecular biological techniques, it is becoming clear that many naturally occurring agents, specifically selected for their tumour growth inhibiting activity, are highly complex and novel substances which are potentially promising as anticancer agents in the clinic. The process of getting a drug from the laboratory bench to the clinic is itself often complex due to adverse physical characteristics of the drug. The experience of the Cancer Research Campaign Clinical Trials Committee in developing several natural products, currently in various stages of development for clinical trial, is described. The drugs discussed include the vinca alkaloids, maytansine, combretastatins, bryostatin 1, pancratistatin, phyllanthoside, dolastatin 10, and taxol.
    Citation
    Medicinal plants in tropical medicine. 2. Natural products in cancer treatment from bench to the clinic., 85 (1):22-5 Trans. R. Soc. Trop. Med. Hyg.
    Journal
    Transactions of the Royal Society of Tropical Medicine and Hygiene
    URI
    http://hdl.handle.net/10541/104755
    DOI
    10.1016/0035-9203(91)90140-T
    PubMed ID
    2068749
    Type
    Article
    Language
    en
    ISSN
    0035-9203
    ae974a485f413a2113503eed53cd6c53
    10.1016/0035-9203(91)90140-T
    Scopus Count
    Collections
    All Paterson Institute for Cancer Research

    entitlement

    Related articles

    • Current Perspectives in the Application of Medicinal Plants Against Cancer: Novel Therapeutic Agents.
    • Authors: Gezici S, Şekeroğlu N
    • Issue date: 2019
    • [Taxol and related diterpenoids of Taxus sp.: important acquisitions in the treatment of cancer].
    • Authors: Vanhaelen MH
    • Issue date: 1992 Sep-Oct
    • Plant products in cancer chemotherapy.
    • Authors: Carter SK, Livingston RB
    • Issue date: 1976 Aug
    • Natural products as a resource for new drugs.
    • Authors: Clark AM
    • Issue date: 1996 Aug
    • Molecular mechanism of herbs in human lung cancer cells.
    • Authors: Kummalue T
    • Issue date: 2005 Nov
    DSpace software (copyright © 2002 - 2023)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.