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Monocytoid B cell lymphoma.

dc.contributor.authorBanerjee, Saumitra S
dc.contributor.authorHarris, Martin
dc.contributor.authorEyden, Brian P
dc.contributor.authorRadford, John A
dc.contributor.authorHarrison, Christine J
dc.contributor.authorMainwaring, A R
dc.date.accessioned2010-06-10T08:27:41Z
dc.date.available2010-06-10T08:27:41Z
dc.date.issued1991-01
dc.identifier.citationMonocytoid B cell lymphoma. 1991, 44 (1):39-44 J. Clin. Pathol.en
dc.identifier.issn0021-9746
dc.identifier.pmid1997532
dc.identifier.doi10.1136/jcp.44.1.39
dc.identifier.urihttp://hdl.handle.net/10541/104580
dc.description.abstractThe clinical, light microscopic, ultrastructural, immunocytochemical and cytogenetic features of a case of monocytoid B cell lymphoma were investigated. The tumour initially affected the cervical and supraclavicular nodes, but 33 months later affected the left parotid salivary gland. The patient had subclinical Sjögren's syndrome. The neoplastic cells showed characteristic morphological features and had peri- and interfollicular distribution in the node. Immunocytochemically the tumour cells were L26, 4KB5, MB2, CD19, CD20, CD22 and IgM/kappa positive. Prominent plasmablastic plasmacytoid differentiation was present in the recurrent tumour, suggesting an origin from post-follicular B cells. The lymphoma cells showed unusual cytogenetic abnormalities.
dc.language.isoenen
dc.subject.meshAdult
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshImmunohistochemistry
dc.subject.meshKaryotyping
dc.subject.meshLymphoma, B-Cell
dc.subject.meshMicroscopy, Electron
dc.subject.meshParotid Gland
dc.subject.meshSjogren's Syndrome
dc.titleMonocytoid B cell lymphoma.en
dc.typeArticleen
dc.contributor.departmentDepartment of Histopathology, Christie Hospital and Holt Radium Institute, Manchester.en
dc.identifier.journalJournal of Clinical Pathologyen
html.description.abstractThe clinical, light microscopic, ultrastructural, immunocytochemical and cytogenetic features of a case of monocytoid B cell lymphoma were investigated. The tumour initially affected the cervical and supraclavicular nodes, but 33 months later affected the left parotid salivary gland. The patient had subclinical Sjögren's syndrome. The neoplastic cells showed characteristic morphological features and had peri- and interfollicular distribution in the node. Immunocytochemically the tumour cells were L26, 4KB5, MB2, CD19, CD20, CD22 and IgM/kappa positive. Prominent plasmablastic plasmacytoid differentiation was present in the recurrent tumour, suggesting an origin from post-follicular B cells. The lymphoma cells showed unusual cytogenetic abnormalities.


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