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    The expression of aphidicolin-induced fragile sites in familial breast cancer patients.

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    Authors
    Mitchell, Erika L D
    Woodhouse, Brian
    Birch, Jillian M
    Santibanez-Koref, Mauro F
    Affiliation
    CRC Department of Cancer Genetics, Paterson Institute for Cancer Research, Manchester, United Kingdom.
    Issue Date
    1993-06
    
    Metadata
    Show full item record
    Abstract
    The expression frequency of aphidicolin-induced fragile sites was examined in familial breast cancer patients to determine whether this parameter could be used as a marker of genetic susceptibility in at-risk individuals. No difference was found in expression frequency between the breast cancer patients and a group of normal individuals (p = 0.61). This indicates that the expression frequency of aphidicolin-induced fragile sites is not a suitable marker for assessing genetic susceptibility in familial breast cancer.
    Citation
    The expression of aphidicolin-induced fragile sites in familial breast cancer patients. 1993, 67 (2):108-12 Cancer Genet. Cytogenet.
    Journal
    Cancer Genetics and Cytogenetics
    URI
    http://hdl.handle.net/10541/100386
    DOI
    10.1016/0165-4608(93)90161-E
    PubMed ID
    8392434
    Type
    Article
    Language
    en
    ISSN
    0165-4608
    ae974a485f413a2113503eed53cd6c53
    10.1016/0165-4608(93)90161-E
    Scopus Count
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    All Paterson Institute for Cancer Research

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