Authors
Teare, M DawnSantibanez-Koref, Mauro F
Wallace, S A
White, Gavin R M
Evans, D Gareth R
Burnell, Liza D
Harris, Martin
Howell, Anthony
Birch, Jillian M
Affiliation
Cancer Research Campaign Pediatric and Familial Cancer Research Group, Christie Hospital, Manchester, England.Issue Date
1993-04
Metadata
Show full item recordAbstract
Seven breast cancer families are examined for evidence of linkage to a site in the region of 17q12-q21, by using five markers. The families constitute a subset of a larger series of familial breast cancer; the seven families were selected because constitutional DNA was available on informative members, either from clinical samples or extracted from paraffin blocks. Two-point lod scores are reported. The maximum lod score, 0.8824, is obtained with marker NM23 at theta = 0. This is clearly not significant in itself; however, when taken in context with evidence from existing reports, it provides support for linkage to this region.Citation
A linkage study in seven breast cancer families. 1993, 52 (4):786-8 Am. J. Hum. Genet.Journal
American Journal of Human GeneticsPubMed ID
8460644Type
ArticleLanguage
enISSN
0002-9297Related articles
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