Common genetic variation associated with increased susceptibility to prostate cancer does not increase risk of radiotherapy toxicity.
Ahmed, M ; Dorling, L ; Kerns, S ; Fachal, L ; Elliott, Rebecca M ; Parliament, M ; Rosenstein, B ; Vega, A ; Gómez-Caamaño, A ; Barnett, G ... show 7 more
Ahmed, M
Dorling, L
Kerns, S
Fachal, L
Elliott, Rebecca M
Parliament, M
Rosenstein, B
Vega, A
Gómez-Caamaño, A
Barnett, G
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Abstract
Numerous germline single-nucleotide polymorphisms increase susceptibility to prostate cancer, some lying near genes involved in cellular radiation response. This study investigated whether prostate cancer patients with a high genetic risk have increased toxicity following radiotherapy.
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Date
2016-05-10
Publisher
Collections
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Type
Article
Citation
Common genetic variation associated with increased susceptibility to prostate cancer does not increase risk of radiotherapy toxicity. 2016, 114 (10):1165-74 Br J Cancer