Extraskeletal myxoid chondrosarcoma with neuroendocrine differentiation: a pathologic, cytogenetic, and molecular study of a case with a novel translocation t(9;17)(q22;q11.2).
Harris, Martin Coyne, John Tariq, M Eyden, Brian P Atkinson, M Freemont, Anthony J Varley, Jennifer Attwooll, C Telford, Nicholas
Harris, Martin
Coyne, John
Tariq, M
Eyden, Brian P
Atkinson, M
Freemont, Anthony J
Varley, Jennifer
Attwooll, C
Telford, Nicholas
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Abstract
A case of extraskeletal myxoid chondrosarcoma (EMC) in which there was histochemical, immunohistochemical, and ultrastructural evidence of neuroendocrine differentiation is reported. Genetic investigations showed the recently described novel translocation t(9;17)(q22;q11.2) and associated fusion of the CHN and RBP56 genes, contrasting with the translocation t(9;22)(q22;q12) and EWS/CHN gene fusion found in the majority of EMCs.
Description
Date
2000-07
Publisher
Keywords
Cancer DNA
Biological Tumour Markers
Soft Tissue Cancer
Biological Tumour Markers
Soft Tissue Cancer
Type
Article
Citation
Extraskeletal myxoid chondrosarcoma with neuroendocrine differentiation: a pathologic, cytogenetic, and molecular study of a case with a novel translocation t(9;17)(q22;q11.2). 2000, 24 (7):1020-6 Am. J. Surg. Pathol.