Clinical applications of interleukin-2.
Von Rohr, A Thatcher, Nick
Von Rohr, A
Thatcher, Nick
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Abstract
Interleukin-2 (IL-2) is a cytokine with potent immunomodulating properties which has shown considerable antitumour activity in preclinical models. In clinical trials, the effects of IL-2 given by various routes and schedules have been investigated. IL-2 has been administered either as single drug or in combination with other cytokines and immunomodulating agents, chemo therapeutic agents, or reinfusions of ex vivo activated autologous cytotoxic effector cells. The results of published clinical studies with IL-2 based immunotherapy are reviewed in this paper.
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Description
Date
1992
Publisher
Collections
Keywords
Tumour-Infiltrating Lymphocytes
Type
Article
Citation
Clinical applications of interleukin-2. 1992, 4 (3):229-46 Prog Growth Factor Res