Nutritional interventions for reducing gastrointestinal toxicity in adults undergoing radical pelvic radiotherapy.
Henson, C Burden, S Davidson, Susan E Lal, S
Henson, C
Burden, S
Davidson, Susan E
Lal, S
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Abstract
Across the developed world, an estimated 150,000 to 300,000 people are treated annually with pelvic radiotherapy and 80% will develop gastrointestinal (GI) symptoms during treatment. Acute GI symptoms are associated with a greater risk of chronic, often debilitating, GI symptoms. Up to one-third of patients are malnourished before pelvic radiotherapy and up to four-fifths of patients lose weight during treatment. Malnutrition is linked to a higher risk of GI toxicity, which can lead to breaks in radiotherapy and early cessation of chemotherapy, thus compromising the efficacy of the primary cancer treatment.
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2013
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Nutritional interventions for reducing gastrointestinal toxicity in adults undergoing radical pelvic radiotherapy. 2013, 11:CD009896 Cochrane Database Syst Rev