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Faslodex (ICI 182780). an oestrogen receptor downregulator.

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Abstract
Anti-oestrogen therapy, tamoxifen in particular, has revolutionised the treatment of breast cancer. However, the partial agonist activity of tamoxifen is associated with an increased risk of endometrial cancer and the acquisition by patients of tamoxifen-resistance. In an attempt overcome these negative aspects of tamoxifen therapy, 'pure' anti-oestrogens have been developed and are currently being investigated for the treatment of breast cancer.
Authors
Howell, Anthony
Affiliation
CRC Department of Medical Oncology, Christie Hospital NHS Trust, M20 4BX, Manchester, UK. maria.parker@christie-tr.nwest.nhs.uk
Description
Date
2000-09
Publisher
Collections
All Christie Publications
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Keywords
Breast Cancer
Oestrogen Receptors
Type
Article
Citation
Faslodex (ICI 182780). an oestrogen receptor downregulator. 2000, 36 Suppl 4:S87-8 Eur. J. Cancer
Journal Title
Journal ISSN
Volume Title
URI
http://hdl.handle.net/10541/86514
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