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Overview of the impact of conventional systemic therapies on breast cancer.

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Abstract
Survival in women with breast cancer is improving in the western world, in part related to improved surgery, radiotherapy and adjuvant systemic therapy. Aromatase inhibitors are superior to tamoxifen in this clinical situation and several studies indicate that taxane-based chemotherapy is superior to non-taxane-based regimens. Herceptin is active alone in HER-2/neu +ve advanced breast cancer and four clinical trials are testing this agent in the adjuvant situation. It seems likely that herceptin will add to conventional therapies and thus will be the paradigm for the introduction of other biological therapies to improve cure rates.
Authors
Howell, Anthony
Wardley, Andrew M
Affiliation
CRUK Department of Medical Oncology, University of Manchester, Christie Hospital, 550 Wilmslow Road, Manchester M20 4BX, UK. Anthony.Howell@christie-tr.nwest.nhs.uk
Description
Date
2005-07
Publisher
Collections
All Christie Publications
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Keywords
Breast Cancer
Type
Article
Citation
Overview of the impact of conventional systemic therapies on breast cancer. 2005, 12 Suppl 1:S9-S16 Endocr. Relat. Cancer
Journal Title
Journal ISSN
Volume Title
URI
http://hdl.handle.net/10541/84452
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