Flow cytometric DNA characteristics of radiation colitis--a preliminary study.
Pearson, J M ; Kumar, Shant ; Butterworth, D M ; Schofield, Philip F ; Haboubi, Najib
Pearson, J M
Kumar, Shant
Butterworth, D M
Schofield, Philip F
Haboubi, Najib
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Abstract
The DNA status of 12 rectal biopsies, taken during the investigation of radiation proctitis, was investigated. Of these six were in the acute phase and six in the chronic phase. All of the acute biopsies had diploid DNA, despite bizarre histological epithelial cell appearances. Two of the chronic phase biopsies were to have aneuploid DNA profiles. This finding may be relevant to the increased risk of malignancy in irradiated tissues.
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Date
1992
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Collections
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Type
Article
Citation
Flow cytometric DNA characteristics of radiation colitis--a preliminary study., 12 (5):1647-9 Anticancer Res