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Evaluation of Prognostic and Predictive Models in the Oncology Clinic
Craddock, M. Crockett, C. McWilliam, A. Price, G. Sperrin, M. van der Veer, S. N. Faivre-Finn, C.
Craddock, M.
Crockett, C.
McWilliam, A.
Price, G.
Sperrin, M.
van der Veer, S. N.
Faivre-Finn, C.
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Abstract
Predictive and prognostic models hold great potential to support clinical decision making in oncology and could ultimately facilitate a paradigm shift to a more personalised form of treatment. While a large number of models relevant to the field of oncology have been developed, few have been translated into clinical use and assessment of clinical utility is not currently considered a routine part of model development. In this narrative review of the clinical evaluation of prediction models in oncology, we propose a high-level process diagram for the life cycle of a clinical model, encompassing model commissioning, clinical implementation and ongoing quality assurance, which aims to bridge the gap between model development and clinical implementation.
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Date
2021
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Citation
Craddock M, Crockett C, McWilliam A, Price G, Sperrin M, van der Veer SN, et al. Evaluation of Prognostic and Predictive Models in the Oncology Clinic. Clin Oncol (R Coll Radiol). 2021.