Loading...
TORPEdO: A phase III trial of intensity-modulated proton beam therapy versus intensity-modulated radiotherapy for multi-toxicity reduction in oropharyngeal cancer
Thomson, David J Cruickshank, C. Baines, H. Banner, R. Beasley, M. Betts, G. Bulbeck, H. Charlwood, Frances Christian, J. Clarke, Matthew
Thomson, David J
Cruickshank, C.
Baines, H.
Banner, R.
Beasley, M.
Betts, G.
Bulbeck, H.
Charlwood, Frances
Christian, J.
Clarke, Matthew
Citations
Altmetric:
Abstract
•There is a lack of prospective level I evidence for the use of PBT for most adult cancers including oropharyngeal squamous cell carcinoma (OPSCC).•TORPEdO is the UK's first PBT clinical trial and aims to determine the benefits of PBT for OPSCC.•Training and support has been provided before and during the trial to reduce variations of contouring and radiotherapy planning.•There is a strong translational component within TORPEdO. Imaging and physics data along with blood, tissue collection will inform future studies in refining patient selection for IMPT.
Authors
Thomson, David J
Cruickshank, C.
Baines, H.
Banner, R.
Beasley, M.
Betts, G.
Bulbeck, H.
Charlwood, Frances
Christian, J.
Clarke, Matthew
Donnelly, O.
Foran, B.
Gillies, C.
Griffin, C.
Homer, J. J.
Langendijk, J. A.
Lee, Lip W
Lester, J.
Lowe, Matthew
McPartlin, A.
Miles, E.
Nutting, C.
Palaniappan, N.
Prestwich, R.
Price, James M
Roberts, Clare
Roe, J.
Shanmugasundaram, R.
Simões, R.
Thompson, A.
West, C.
Wilson, Lorna
Wolstenholme, J.
Hall, E.
Cruickshank, C.
Baines, H.
Banner, R.
Beasley, M.
Betts, G.
Bulbeck, H.
Charlwood, Frances
Christian, J.
Clarke, Matthew
Donnelly, O.
Foran, B.
Gillies, C.
Griffin, C.
Homer, J. J.
Langendijk, J. A.
Lee, Lip W
Lester, J.
Lowe, Matthew
McPartlin, A.
Miles, E.
Nutting, C.
Palaniappan, N.
Prestwich, R.
Price, James M
Roberts, Clare
Roe, J.
Shanmugasundaram, R.
Simões, R.
Thompson, A.
West, C.
Wilson, Lorna
Wolstenholme, J.
Hall, E.
Affiliation
Description
Date
2023
Publisher
Collections
Files
Keywords
Type
Article
Citation
Thomson DJ, Cruickshank C, Baines H, Banner R, Beasley M, Betts G, et al. TORPEdO: A phase III trial of intensity-modulated proton beam therapy versus intensity-modulated radiotherapy for multi-toxicity reduction in oropharyngeal cancer. Clinical and translational radiation oncology. 2023 Jan;38:147-54. PubMed PMID: 36452431. Pubmed Central PMCID: PMC9702982 personal relationships that could have appeared to influence the work reported in this paper. Epub 2022/12/02. eng.