Lack of a relationship between colony-forming efficiency and surviving fraction at 2 Gy.
West, Catharine M L Davidson, Susan E Pool, Claire James, Roger D Schofield, Philip F
West, Catharine M L
Davidson, Susan E
Pool, Claire
James, Roger D
Schofield, Philip F
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Abstract
The relationship between in vitro radiation sensitivity and colony-forming efficiency has been examined for primary human tumors of the cervix, colorectum, and lymph gland. Tumors were cultured using the Courtenay-Mills soft agar clonogenic assay and radiosensitivity was assessed as surviving fraction at 2 Gy. There was no correlation between colony-forming efficiency and surviving fraction at 2 Gy, giving confidence to the use of surviving fraction at 2 Gy as a predictor of clinical outcome.
Description
Date
1991-05
Publisher
Keywords
Cancer
Colonic Cancer
Rectal Cancer
Tumour Stem Cell Assay
Uterine Cervical Cancer
Colonic Cancer
Rectal Cancer
Tumour Stem Cell Assay
Uterine Cervical Cancer
Type
Article
Citation
Lack of a relationship between colony-forming efficiency and surviving fraction at 2 Gy. 1991, 126 (2):260-3 Radiat. Res.