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Genome wide association study of acute radiation toxicity and quality of life in breast cancer patients - results from the REQUITE cohort study
Rattay, T. Veal, C. D. Azria, D. Chang-Claude, J. Davidson, Susan E Dunning, A. De Ruysscher, D Fachal, L. Gutierrez-Enriquez, S. Lambin, P.
Rattay, T.
Veal, C. D.
Azria, D.
Chang-Claude, J.
Davidson, Susan E
Dunning, A.
De Ruysscher, D
Fachal, L.
Gutierrez-Enriquez, S.
Lambin, P.
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Abstract
Background: Around a quarter of breast cancer patients treated by surgery and radiotherapy experienceclinically significant toxicity, which may adversely affect breast cosmesis and qualityof life (QoL). If patients at high risk of toxicity could be identified at diagnosis,this could be taken into account when discussing treatment options. This study wasdesigned to identify common single nucleotide polymorphisms (SNPs) associated withacute radiation toxicity and change in QoL on completion of radiotherapy.
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Date
2020
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Type
Meetings and Proceedings
Citation
Rattay T, Veal CD, Azria D, Chang-Claude J, Davidson S, Dunning A, et al. Genome wide association study of acute radiation toxicity and quality of life in breast cancer patients – results from the REQUITE cohort study. European Journal of Cancer. 2020;138:S12-S.