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Trifluridine/tipiracil versus placebo in patients with heavily pretreated metastatic gastric cancer (TAGS): a randomised, double-blind, placebo-controlled, phase 3 trial.

Shitara, K
Doi, T
Dvorkin, M
Mansoor, Was
Arkenau, H
Prokharau, A
Alsina, M
Ghidini, M
Faustino, C
Gorbunova, V
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Abstract
Trifluridine/tipiracil showed activity and was well tolerated in a phase 2 study of pretreated patients with advanced gastric cancer done in Japan. We investigated whether the treatment was efficacious compared with placebo in a global population.
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2018
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Article
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Trifluridine/tipiracil versus placebo in patients with heavily pretreated metastatic gastric cancer (TAGS): a randomised, double-blind, placebo-controlled, phase 3 trial. 2018 Lancet Oncol
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