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New insights into the mechanisms of action of radioimmunotherapy in lymphoma.

Ivanov, Andrei
Swann, Ruth
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Abstract
The exquisite sensitivity of haematological malignancies to targeted radiation alongside the impressive results achieved by the pioneers in this field suggests that radioimmunotherapy is likely to be a productive area for future clinical research. Recent experimental work has demonstrated that the combination of targeted radiation and antibody effector mechanisms are critical to long-term clearance of tumour. This review provides the background of clinical and biological insights into the mechanisms of action of radioimmunotherapy.
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2008-08
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Article
Citation
New insights into the mechanisms of action of radioimmunotherapy in lymphoma. 2008, 60 (8):987-98 J. Pharm. Pharmacol.
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