Immunohistochemical detection of steroid receptors in breast cancer: a working protocol.
Leake, Robin Barnes, Diana M Pinder, Sarah Ellis, Ian Anderson, Elizabeth Anderson, Tom Adamson, Ruth Rhodes, Anthony Miller, Keith D Walker, Rosemary
Leake, Robin
Barnes, Diana M
Pinder, Sarah
Ellis, Ian
Anderson, Elizabeth
Anderson, Tom
Adamson, Ruth
Rhodes, Anthony
Miller, Keith D
Walker, Rosemary
Citations
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Abstract
The biochemical assay for the oestrogen receptor has shown the clinical value of knowing the concentration of the receptor within tissue. The immunohistochemical assay is rapidly taking over from the biochemical assay. Therefore, it is vital to have an equivalent scoring system that will have the same predictive value. This paper reports both a practical protocol and a scoring system that should achieve this aim. This approach should be applicable to many more biomarkers detected by immunohistochemistry.
Description
Date
2000-08
Publisher
Collections
Keywords
Breast Cancer
Biological Tumour Markers
Oestrogen Receptors
Biological Tumour Markers
Oestrogen Receptors
Type
Article
Citation
Immunohistochemical detection of steroid receptors in breast cancer: a working protocol. 2000, 53 (8):634-5 J. Clin. Pathol.