Heritability of chromosomal radiosensitivity in breast cancer patients: a pilot study with the lymphocyte micronucleus assay.
Burrill, Wayne Barber, James B P Roberts, Stephen A Bulman, Barbara Scott, David
Burrill, Wayne
Barber, James B P
Roberts, Stephen A
Bulman, Barbara
Scott, David
Citations
Altmetric:
Abstract
Of breast cancer patients, 30% are sensitive in a lymphocyte assay of radiation-induced chromosome damage (micronucleus induction) compared with 10% of healthy controls. Twenty-two first-degree relatives of 11 sensitive patients had an average micronucleus yield significantly higher than that of 68 controls. This suggests that radiosensitivity in this assay may be an inherited characteristic associated with predisposition to breast cancer.
Description
Date
2000-12
Publisher
Collections
Keywords
Breast Cancer
Type
Article
Citation
Heritability of chromosomal radiosensitivity in breast cancer patients: a pilot study with the lymphocyte micronucleus assay. 2000, 76 (12):1617-9 Int. J. Radiat. Biol.