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Sarcomas in three generations of a family with neurofibromatosis.
Hartley, Ann L Birch, Jillian M Kelsey, Anna M Harris, Martin Jones, P H
Hartley, Ann L
Birch, Jillian M
Kelsey, Anna M
Harris, Martin
Jones, P H
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Abstract
The development of sarcomas in three generations of a family with neurofibromatosis (NF) is described. A 7-month-old boy developed a prostatic rhabdomyosarcoma. Family history revealed that his maternal grandmother had died of a malignant peripheral nerve sheath tumor at age 37 years and had been affected with neurofibromatosis. His mother (aged 36 years) has also developed a malignant peripheral nerve sheath tumor and NF has been confirmed in both mother and son. This family illustrates a cluster of sarcomas associated with NF and shows the importance of thorough investigation of reported family illnesses.
Description
Date
1990-04
Publisher
Collections
Keywords
Hereditary Cancerous Syndromes
Peripheral Nervous System Cancer
Prostatic Cancer
Peripheral Nervous System Cancer
Prostatic Cancer
Type
Article
Citation
Sarcomas in three generations of a family with neurofibromatosis. 1990, 45 (2):245-8 Cancer Genet Cytogenet