Mesoblastic nephroma contains fibronectin but lacks laminin.
Kumar, Shant Marsden, Henry B Carr, T Kodet, R
Kumar, Shant
Marsden, Henry B
Carr, T
Kodet, R
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Abstract
Non-metastatic mesoblastic nephromas from four young children were shown to contain fibronectin but not laminin using an immunoperoxidase staining procedure. In contrast, one metastasising spindle celled sarcomatous tumour from a neonate was laminin positive. During embryogenesis primitive nephrogenic mesenchyme contains only fibronectin and no laminin; metanephric blastema (permanent kidney) is positive for laminin. The staining for fibronectin and laminin may help to ascertain the histogenesis of different types of renal tumour.
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Affiliation
Description
Date
1985-05
Publisher
Collections
Keywords
Kidney Cancer
Wilms Tumour
Wilms Tumour
Type
Article
Citation
Mesoblastic nephroma contains fibronectin but lacks laminin. 1985, 38 (5):507-11 J Clin Pathol