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Digital histology quantification of intra-hepatic fat in patients undergoing liver resection.
Parkin, E O'Reilly, D Plumb, Andrew A Manoharan, Prakash Rao, M Coe, P Frystyk, J Ammori, B de Liguori Carino, N Deshpande, R
Parkin, E
O'Reilly, D
Plumb, Andrew A
Manoharan, Prakash
Rao, M
Coe, P
Frystyk, J
Ammori, B
de Liguori Carino, N
Deshpande, R
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Abstract
High intra-hepatic fat (IHF) content is associated with insulin resistance, visceral adiposity, and increased morbidity and mortality following liver resection. However, in clinical practice, IHF is assessed indirectly by pre-operative imaging [for example, chemical-shift magnetic resonance (CS-MR)]. We used the opportunity in patients undergoing liver resection to quantify IHF by digital histology (D-IHF) and relate this to CT-derived anthropometrics, insulin-related serum biomarkers, and IHF estimated by CS-MR.
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Date
2015-08
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Article
Citation
Digital histology quantification of intra-hepatic fat in patients undergoing liver resection. 2015, 41 (8):1020-7 Eur J Surg Oncol