Evaluation of hypertension and proteinuria as markers of efficacy in antiangiogenic therapy for metastatic colorectal cancer.
Khoja, Leila Kumaran, Gireesh C Zee, Ying-Kiat Murukesh, Nishanth Swindell, Ric Saunders, Mark P Clamp, Andrew R Wilson, Gregory
Khoja, Leila
Kumaran, Gireesh C
Zee, Ying-Kiat
Murukesh, Nishanth
Swindell, Ric
Saunders, Mark P
Clamp, Andrew R
Wilson, Gregory
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Abstract
The vascular endothelial growth factor pathway is strongly implicated in cancer-related angiogenesis. Antiangiogenic agents such as bevacizumab commonly cause hypertension (HTN) and proteinuria (PTN), which may be biomarkers of response and clinical outcome.
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Date
2013-10-22
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Article
Citation
Evaluation of hypertension and proteinuria as markers of efficacy in antiangiogenic therapy for metastatic colorectal cancer. 2013: J Clin Gastroenterol