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Pre-treatment tumour perfusion parameters and initial RECIST response do not predict long-term survival outcomes for patients with head and neck squamous cell carcinoma treated with induction chemotherapy.
Lowe, Natalie M Kershaw, Lucy E Bernstein, Jonathan M Withey, S Mais, Kathleen L Homer, Jarrod J Bonington, Suzanne C Carrington, Bernadette M
Lowe, Natalie M
Kershaw, Lucy E
Bernstein, Jonathan M
Withey, S
Mais, Kathleen L
Homer, Jarrod J
Bonington, Suzanne C
Carrington, Bernadette M
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Abstract
Previously, we showed that pre-treatment tumour plasma perfusion (Fp) predicts RECIST response to induction chemotherapy (ICT) in locoregionally advanced head and neck squamous cell carcinoma (HNSCC). The aim here was to determine whether the pre-treatment tumour Fp estimate, changes in tumour Fp or RECIST response post 2 cycles of ICT were prognostic for long-term survival outcomes.
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2018
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Pre-treatment tumour perfusion parameters and initial RECIST response do not predict long-term survival outcomes for patients with head and neck squamous cell carcinoma treated with induction chemotherapy. 2018, 13 (3):e0194841 PLoS One