Intraparenchymal myofibromatosis of the brain in an adult: report of an unusual case.
Xiao, Hua-Liang Eyden, Brian P Yan, Xiao-Chu Wang, Yi Zhang, Rong Bian, Xiu-Wu
Xiao, Hua-Liang
Eyden, Brian P
Yan, Xiao-Chu
Wang, Yi
Zhang, Rong
Bian, Xiu-Wu
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Abstract
An unusual case of intraparenchymal myofibromatosis of the brain occurring in a 29-year-old woman is described. Preoperative CT and MRI examinations revealed two well-circumscribed nodular masses localized in the wall of the left lateral ventricle and right temporal lobe, respectively. Both masses were completely resected, and the patient remains disease-free 2 years post-surgery. Histopathologically, the lesions were characterized by stratification. From outer to inner, there was a reactive glial component, lamellated well-differentiated muscle-like cells, densely compact collagen fibers and cellular tumor with nodular and hemangiopericytoma-like patterns, respectively. The myofibroblastic nature of this tumor was verified by immunohistochemical staining and ultrastructural analysis. Intraparenchymal myofibromatosis may be confused with, and should be distinguished from, meningioma, myopericytoma, solitary fibrous tumor, leiomyoma and inflammatory myofibroblastic tumor for accurate diagnosis and optimal treatment.
Description
Date
2010-06
Publisher
Collections
Keywords
Brain Tumour
Intraparenchymal Myofibromatosis
Intraparenchymal Myofibromatosis
Type
Article
Citation
Intraparenchymal myofibromatosis of the brain in an adult: report of an unusual case. 2010, 30 (3):288-93 Neuropathology