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Enhanced stability of microRNA expression facilitates classification of FFPE tumour samples exhibiting near total mRNA degradation.

Hall, J S
; 
Taylor, J
; 
Valentine, Helen R
; 
Irlam, Joely J
; 
Eustace, A
; 
Hoskin, P J
; 
Miller, Crispin J
; 
West, Catharine M L
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Abstract
As degradation of formalin-fixed paraffin-embedded (FFPE) samples limits the ability to profile mRNA expression, we explored factors predicting the success of mRNA expression profiling of FFPE material and investigated an approach to overcome the limitation.
Authors
Hall, J S
Taylor, J
Valentine, Helen R
Irlam, Joely J
Eustace, A
Hoskin, P J
Miller, Crispin J
West, Catharine M L
Affiliation
Translational Radiobiology Group, School of Cancer and Enabling Sciences, Manchester Academic Health Science Centre, The University of Manchester, Christie Hospital NHS Trust, Wilmslow Road, Manchester M20 4BX, UK.
Description
Date
2012-08-07
Publisher
Collections
All Paterson Institute for Cancer Research
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Type
Article
Citation
Enhanced stability of microRNA expression facilitates classification of FFPE tumour samples exhibiting near total mRNA degradation. 2012, 107 (4):684-94 Br J Cancer
Journal Title
Journal ISSN
Volume Title
URI
http://hdl.handle.net/10541/254617
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