A phase II trial evaluating two schedules of sagopilone (ZK-EPO), a novel epothilone, in patients with platinum-resistant ovarian cancer.
Rustin, G ; Reed, N ; Jayson, Gordon C ; Ledermann, J A ; Adams, M ; Perren, T ; Poole, C ; Lind, M ; Persic, M ; Essapen, S ... show 6 more
Rustin, G
Reed, N
Jayson, Gordon C
Ledermann, J A
Adams, M
Perren, T
Poole, C
Lind, M
Persic, M
Essapen, S
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Abstract
Sagopilone, the first fully synthetic epothilone, has shown promising preclinical activity in tumour models. This open-label randomised phase II study investigated two infusion schedules of sagopilone in women with ovarian cancer.
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Date
2011-11
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Article
Citation
A phase II trial evaluating two schedules of sagopilone (ZK-EPO), a novel epothilone, in patients with platinum-resistant ovarian cancer. 2011, 22 (11):2411-6 Ann Oncol