The psychosocial impact of human papillomavirus testing in primary cervical screening-a study within a randomized trial.
Kitchener, Henry C Fletcher, I Roberts, Caleb Wheeler, P Almonte, M Maguire, Peter
Kitchener, Henry C
Fletcher, I
Roberts, Caleb
Wheeler, P
Almonte, M
Maguire, Peter
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Abstract
The purpose of the study was to assess the psychosocial impact of human papillomavirus (HPV) testing as an adjunct to cytology in routine primary cervical screening. A controlled study of the psychosocial impact of HPV testing within a randomized trial of HPV testing to assess its efficacy in cervical screening was carried out. The trial provides a randomized setting of revealed HPV results versus concealed results permitting valid comparisons for assessing true psychosocial impact. The setting comprised a large number of general practices in primary care. Women aged 20-64 years who underwent routine cervical screening participated in the study. The intervention was a revealed high-risk HPV test result in addition to cervical cytology. The main outcome was measured using General Health Questionnaire (GHQ-28), Spielberger State-Trait Anxiety Inventory, and Sexual Rating Scale (SRS). Among women with either mildly abnormal or normal cytology, receiving an HPV(+ve) result did not impact significantly on GHQ caseness and mean scores or on Spielberger State and Trait scores when compared with women in whom the HPV(+ve) test result was concealed. Among women with normal cytology, receiving an HPV(+ve) result was associated with a reduction in the Sexual Rating Scale compared with similar women whose HPV(+ve) result was concealed. HPV testing does not add significant psychologic distress when combined with cytology in routine primary cervical screening.
Description
Date
2009-04-01T22:53:34Z
Publisher
Collections
Keywords
Human Papillomavirus
Cervical Screening
HPV
Cervical Screening
HPV
Type
Article
Citation
The psychosocial impact of human papillomavirus testing in primary cervical screening-a study within a randomized trial., 18 (4):743-8 Int. J. Gynecol. Cancer