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A phase I study of nintedanib combined with cisplatin/gemcitabine as first-line therapy for advanced squamous non-small cell lung cancer (LUME-Lung 3).
Forster, M ; Hackshaw, A ; De Pas, T ; Cobo, M ; Garrido, P ; Summers, Yvonne J ; Dingemans, A ; Flynn, M ; Schnell, D ; von Wangenheim, U ... show 3 more
Forster, M
Hackshaw, A
De Pas, T
Cobo, M
Garrido, P
Summers, Yvonne J
Dingemans, A
Flynn, M
Schnell, D
von Wangenheim, U
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Abstract
There are limited treatment options for squamous non-small cell lung cancer (sqNSCLC) and prognosis remains poor. The safety and pharmacokinetics (PK) of nintedanib, a triple angiokinase inhibitor, plus cisplatin/gemcitabine as first-line treatment for advanced sqNSCLC patients, were evaluated.
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Date
2018-06
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A phase I study of nintedanib combined with cisplatin/gemcitabine as first-line therapy for advanced squamous non-small cell lung cancer (LUME-Lung 3). 2018, 120: 27-33 Lung Cancer