Predictive factors for failure to identify sentinel nodes in head and neck squamous cell carcinoma.
Hornstra, Marije T Alkureishi, Lee W T Ross, Gary L Shoaib, Taimur Soutar, David S
Hornstra, Marije T
Alkureishi, Lee W T
Ross, Gary L
Shoaib, Taimur
Soutar, David S
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Abstract
BACKGROUND: The aim of this study was to ascertain which factors determine success of sentinel node biopsy (SNB). METHODS: We conducted a retrospective review of 121 patients with head and neck squamous cell carcinoma undergoing SNB to stage the neck. All patients underwent the triple-diagnostic procedure of preoperative lymphoscintigraphy, intraoperative blue dye, and a gamma probe. Factors contributing to failure of SNB were identified. RESULTS: SNB was unsuccessful in 12 of 121 patients (10%). Seven of the 12 patients had cT1/cT2 tumors, and 6 of these were located in the floor of mouth. SN identification was more likely to be successful in patients with cN0 necks, but this did not reach statistical significance (92% vs 84%, p = .268). Factors associated with failure included T classification (p = .01), tumor site (p = .05), and negative preoperative lymphoscintigraphy (p = .0174). CONCLUSION: Successful sentinel lymph node harvest is related to primary tumor site, T classification, and the presence of nodes on preoperative lymphoscintigraphy.
Description
Date
2008-07
Publisher
Collections
Keywords
Squamous Cell
Head and Neck Cancer
Mouth Cancer
Head and Neck Cancer
Mouth Cancer
Type
Article
Citation
Predictive factors for failure to identify sentinel nodes in head and neck squamous cell carcinoma. 2008, 30 (7):858-62 Head Neck