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Bevacizumab plus Capecitabine versus Capecitabine alone in elderly patients with previously untreated metastatic colorectal cancer (AVEX): an open-label, randomised phase 3 trial.
Cunningham, D Lang, I Marcuello, E Lorusso, V Ocvirk, J Shin, D Jonker, D Osborne, S Andre, N Waterkamp, D
Cunningham, D
Lang, I
Marcuello, E
Lorusso, V
Ocvirk, J
Shin, D
Jonker, D
Osborne, S
Andre, N
Waterkamp, D
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Abstract
Elderly patients are often under-represented in clinical trials of metastatic colorectal cancer. We aimed to assess the efficacy and safety of bevacizumab plus capecitabine compared with capecitabine alone in elderly patients with metastatic colorectal cancer.
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2013-10
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Bevacizumab plus Capecitabine versus Capecitabine alone in elderly patients with previously untreated metastatic colorectal cancer (AVEX): an open-label, randomised phase 3 trial. 2013, 14 (11):1077-85 Lancet Oncol