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Regional assignment by hybrid mapping of 36 expressed sequence tags (ESTs) on human chromosome 6.
Pappas, G J Polymeropoulos, M H Boyle, John M Trent, J M
Pappas, G J
Polymeropoulos, M H
Boyle, John M
Trent, J M
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Abstract
We have determined the regional chromosome assignment of 36 cDNAs from infant brain libraries by assessing the concordant segregation of PCR products using a human-rodent hybrid mapping panel that subdivides chromosome 6 into 15 regions. These mapped sequences serve as markers for the physical and expression maps of chromosome 6, as well as candidate genes for various disease loci. Sequence analysis has identified putative functions and motifs for some of these genes.
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Date
1995-01-01
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Article
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Regional assignment by hybrid mapping of 36 expressed sequence tags (ESTs) on human chromosome 6. 1995, 25 (1):124-9 Genomics