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The role of steroid hormones in breast and effects on cancer stem cells.

Alférez, Denis G
; 
Simões, Bruno M
; 
Howell, Sacha J
; 
Clarke, Robert B
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Abstract
This review will discuss how the steroid hormones, estrogen and progesterone, as well as treatments that target steroid receptors, can regulate cancer stem cell (CSC) activity. The CSC theory proposes a hierarchical organization in tumors where at its apex lies a subpopulation of cancer cells endowed with self-renewal and differentiation capacity.
Authors
Alférez, Denis G
Simões, Bruno M
Howell, Sacha J
Clarke, Robert B
Affiliation
Breast Biology Group, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine, and Health, Manchester Cancer Research Centre, Wilmslow Road, Manchester, M20 4GJ
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Date
2018
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All Christie Publications
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Article
Citation
The role of steroid hormones in breast and effects on cancer stem cells. 2018, 4 (1):81-94 Curr Stem Cell Rep
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URI
http://hdl.handle.net/10541/620965
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