Early reduction in tumour [18F]fluorothymidine (FLT) uptake in patients with non-small cell lung cancer (NSCLC) treated with radiotherapy alone.
Trigonis, I Koh, P Taylor, Benjamin Tamal, M Ryder, W David J Earl, Mark Anton-Rodriguez, J Haslett, Kate Young, H
Trigonis, I
Koh, P
Taylor, Benjamin
Tamal, M
Ryder, W David J
Earl, Mark
Anton-Rodriguez, J
Haslett, Kate
Young, H
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Abstract
Changes in tumour 3'-deoxy-3'-[(18)F]fluorothymidine (FLT) uptake during concurrent chemo-radiotherapy in patients with non-small cell lung cancer (NSCLC) have been reported, at variable time points, in two pilot positron emission tomography (PET) studies. The aim of this study was to assess whether FLT changes occur early in response to radiotherapy (RT) without concurrent chemotherapy and whether such changes exceed test-retest variability.
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Date
2014-04
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Early reduction in tumour [18F]fluorothymidine (FLT) uptake in patients with non-small cell lung cancer (NSCLC) treated with radiotherapy alone. 2014, 41 (4):682-93 Eur J Nucl Med Mol Imaging