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The differential effects of statins on the metastatic behaviour of prostate cancer.

Brown, Michael D
; 
Hart, C
; 
Tawadros, T
; 
Ramani, Vijay A C
; 
Sangar, Vijay K
; 
Lau, Maurice W
; 
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Abstract
Although statins do not affect the incidence of prostate cancer (CaP), usage reduces the risk of clinical progression and mortality. Although statins are known to downregulate the mevalonate pathway, the mechanism by which statins reduce CaP progression is unknown.
Authors
Brown, Michael D
Hart, C
Tawadros, T
Ramani, Vijay A C
Sangar, Vijay K
Lau, Maurice W
Clarke, Noel W
Affiliation
Genito Urinary Cancer Research Group, University of Manchester, Paterson Institute for Cancer Research, Manchester Academic Health Science Centre, The Christie NHS Foundation Trust, Wilmslow Road, Withington, Manchester M20 4BX, UK. mbrown@picr.man.ac.uk
Description
Date
2012-05-08
Publisher
Collections
All Christie Publications
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Type
Article
Citation
The differential effects of statins on the metastatic behaviour of prostate cancer. 2012, 106 (10):1689-96 Br J Cancer
Journal Title
Journal ISSN
Volume Title
URI
http://hdl.handle.net/10541/251860
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