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Dynamic contrast-enhanced MRI in patients with muscle-invasive transitional cell carcinoma of the bladder can distinguish between residual tumour and post-chemotherapy effect.
Donaldson, Stephanie B ; Bonington, Suzanne C ; Kershaw, Lucy E ; Cowan, Richard A ; Lyons, Jeanette ; Elliott, Tony ; Carrington, Bernadette M
Donaldson, Stephanie B
Bonington, Suzanne C
Kershaw, Lucy E
Cowan, Richard A
Lyons, Jeanette
Elliott, Tony
Carrington, Bernadette M
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Abstract
Treatment of muscle-invasive bladder cancer with chemotherapy results in haemorrhagic inflammation, mimicking residual tumour on conventional MR images and making interpretation difficult. The aim of this study was to use dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to estimate descriptive and tracer kinetic parameters post-neoadjuvant chemotherapy and to investigate whether parameters differed in areas of residual tumour and chemotherapy-induced haemorrhagic inflammation (treatment effect, Tr-Eff).
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2013-08-15
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Citation
Dynamic contrast-enhanced MRI in patients with muscle-invasive transitional cell carcinoma of the bladder can distinguish between residual tumour and post-chemotherapy effect. 2013: Eur J Radiol