Serum cortisol: an up-to-date assessment of routine assay performance.
Hawley, J Owen, L Lockhart, S Monaghan, Phillip J Armston, A Chadwick, C Wilshaw, H Freire, M Perry, L Keevil, B
Hawley, J
Owen, L
Lockhart, S
Monaghan, Phillip J
Armston, A
Chadwick, C
Wilshaw, H
Freire, M
Perry, L
Keevil, B
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Abstract
Accurate serum cortisol quantification is required for the correct diagnosis and management of adrenal pathologies. Presently, most laboratories use immunoassay to measure serum cortisol with proficiency schemes demonstrating a wide dispersion of results. Here, we investigate the effects of sex, matrix, and antibody specificity on serum cortisol quantification in 6 routine assays.
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Date
2016-07-20
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Citation
Serum cortisol: an up-to-date assessment of routine assay performance. 2016: Clin. Chem.