Efficient and reproducible generation of tumour-infiltrating lymphocytes for renal cell carcinoma.
Baldan, Vania ; Griffiths, R ; Hawkins, Robert E ; Gilham, David E
Baldan, Vania
Griffiths, R
Hawkins, Robert E
Gilham, David E
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Abstract
Tumour-infiltrating lymphocyte (TIL) therapy is showing great promise in the treatment of patients with advanced malignant melanoma. However, the translation of TIL therapy to non-melanoma tumours such as renal cell carcinoma has been less successful with a major constraint being the inability to reproducibly generate TILs from primary and metastatic tumour tissue.
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2015-04-28
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Efficient and reproducible generation of tumour-infiltrating lymphocytes for renal cell carcinoma. 2015, 112 (9):1510-8 Br J Cancer