Phase I pharmacokinetic and pharmacodynamic study of the bioreductive drug RH1.
Danson, Sarah Johnson, P Ward, Timothy H Dawson, M Denneny, Olive Dickinson, G Aarons, Leon Watson, A Jowle, Debra Cummings, Jeffrey
Danson, Sarah
Johnson, P
Ward, Timothy H
Dawson, M
Denneny, Olive
Dickinson, G
Aarons, Leon
Watson, A
Jowle, Debra
Cummings, Jeffrey
Citations
Altmetric:
Abstract
This trial describes a first-in-man evaluation of RH1, a novel bioreductive drug activated by DT-diaphorase (DTD), an enzyme overexpressed in many tumours.
Description
Date
2011-07
Publisher
Keywords
Type
Article
Citation
Phase I pharmacokinetic and pharmacodynamic study of the bioreductive drug RH1. 2011, 22 (7):1653-60 Ann. Oncol.